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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WHSC1
All Species:
14.55
Human Site:
Y175
Identified Species:
35.56
UniProt:
O96028
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96028
NP_001035889.1
1365
152258
Y175
N
R
K
R
S
I
K
Y
D
S
L
L
E
Q
G
Chimpanzee
Pan troglodytes
XP_001146084
1365
152240
Y175
N
R
K
R
S
I
K
Y
D
S
L
L
E
Q
G
Rhesus Macaque
Macaca mulatta
XP_001091062
1390
155951
E223
I
P
K
L
E
P
E
E
Q
N
R
P
N
E
R
Dog
Lupus familis
XP_536224
1302
145396
G162
H
L
L
K
Y
N
V
G
D
L
V
W
S
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVE8
1365
152234
Y175
N
R
K
R
S
I
K
Y
D
S
L
L
E
Q
G
Rat
Rattus norvegicus
XP_001058474
1365
152585
Y175
N
R
K
R
S
I
K
Y
D
S
L
L
E
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516412
936
104874
Chicken
Gallus gallus
XP_420839
1369
154617
D176
R
K
R
S
I
K
Y
D
S
L
L
E
Q
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076020
1461
163773
T238
G
D
M
P
T
C
V
T
A
F
P
D
E
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT36
1427
159010
F214
S
S
P
N
S
T
G
F
E
A
G
S
E
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
43.5
87.9
N.A.
90.9
90.1
N.A.
55
80.3
N.A.
46.6
N.A.
26
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
59.3
90.9
N.A.
94.4
94.3
N.A.
60.4
88.3
N.A.
60.5
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
100
100
N.A.
0
6.6
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
100
N.A.
0
26.6
N.A.
20
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
50
0
0
10
0
10
0
% D
% Glu:
0
0
0
0
10
0
10
10
10
0
0
10
60
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
10
0
0
10
0
0
10
40
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
40
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
50
10
0
10
40
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
10
10
0
0
0
0
0
20
50
40
0
0
20
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
10
0
10
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
10
10
10
0
10
0
0
0
0
10
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
50
0
% Q
% Arg:
10
40
10
40
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
10
10
0
10
50
0
0
0
10
40
0
10
10
0
0
% S
% Thr:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
20
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _